Journal of critical care
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Journal of critical care · Dec 2018
Review Meta AnalysisEffect of adjunctive corticosteroids on clinical outcomes in adult patients with septic shock - a meta-analysis of randomized controlled trials and trial sequential analysis.
To assess the effect of corticosteroids on clinical outcomes in patients with septic shock. ⋯ Future trials are unlikely to detect a reduction in short-term mortality at a daily doses of 200 mg hydrocortisone. More evidence is required to confirm the beneficial effects of dual corticosteroid therapy.
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Journal of critical care · Dec 2018
Meta AnalysisEffect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis.
We aimed to classify nonpharmacological interventions used for preventing delirium in the intensive care unit (ICU), and estimate their effect size. ⋯ Nonpharmacological interventions were effective in reducing the duration and occurrence of delirium. Consistent application and development of nonpharmacological interventions for use in the ICU are important.
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Journal of critical care · Dec 2018
Meta AnalysisPrognostic value of plasma brain natriuretic peptide value for patientswith sepsis: A meta-analysis.
The aim of this meta-analysis was to clarify the diagnostic role of plasma BNP and NT-proBNP in predicting mortality for septic patients. ⋯ This meta-analysis indicates that both elevated plasma BNP and NT-proBNP have moderate predicts value for the mortality of septic patients, and the tested method and observation endpoint influence the results of BNP.