Journal of critical care
-
Journal of critical care · Jun 2019
Observational StudyA worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit.
To investigate age-related differences in outcomes of critically ill patients with sepsis around the world. ⋯ The odds for death in ICU patients with sepsis increased with age with the maximal rate of increase occurring between the ages of 71 and 77 years.
-
Journal of critical care · Jun 2019
Diastolic pressure should be used to guide management of patients in shock: PRO.
Based primarily on the rational that adequate diastolic pressure is needed to maintain sufficient coronary blood for myocardial needs, diastolic pressure has been proposed as a treatment target for patients in shock. To date, clinical evidence supporting this is limited to observational data. ⋯ Targeting diastolic pressure can lead to over use of vasopressors, which studies have associated with worse outcome. Pressor management in shock should include assessment of indicators of tissue perfusion and changes in flow if possible.
-
Journal of critical care · Jun 2019
Editorial Retraction Of PublicationTEMPORARY REMOVAL: Importance of diastolic arterial pressure in septic shock: PRO.
-
Journal of critical care · Jun 2019
Multicenter Study Observational StudyAdherence to fluid resuscitation guidelines and outcomes in patients with septic shock: Reassessing the "one-size-fits-all" approach.
The Surviving Sepsis Campaign and Centers for Medicare and Medicaid Services (CMS) Severe Sepsis and Septic Shock Management Bundle (SEP-1) recommend rapid crystalloid infusion (≥30 mL/kg) for patients with sepsis-induced hypoperfusion or septic shock. We aimed to assess compliance with this recommendation, factors associated with non-compliance, and how compliance relates to mortality. ⋯ These findings question a "one-size-fits-all" approach to fluid administration and performance measures for patients with sepsis.
-
Journal of critical care · Jun 2019
Multicenter Study Observational StudyHuman atrial natriuretic peptide for acute kidney injury in adult critically ill patients: A multicenter prospective observational study.
Acute kidney injury (AKI) is common in the intensive care unit (ICU). Selected clinical studies have implied human atrial natriuretic peptide (hANP) improves renal function; however, the treatment effects for AKI are unclear. ⋯ In critically ill patients with AKI, the treatment effect of hANP was not evident on dialysis-free survival in the ICU.