Journal of critical care
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Journal of critical care · Aug 2019
Observational StudyThe incidence, characteristics, outcomes and associations of small short-term point-of-care creatinine increases in critically ill patients.
We assessed the incidence, characteristics, outcomes and associations of small, short-term point-of-care creatinine increases in critically ill patients. ⋯ Small, short-term point-of-care creatinine increase episodes are common. They are associated with illness severity, occur early, precede AKI by 10 h and are sensitive rather than specific markers of AKI.
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Journal of critical care · Aug 2019
Serum glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 for diagnosis of sepsis-associated encephalopathy and outcome prognostication.
We investigated the role of serum Glial Fibrillary Acidic Protein (GFAP) and Ubiquitin C-Terminal Hydrolase-L1 (UCH-L1) in diagnosis of sepsis-associated encephalopathy(SAE), predicting prognosis and long-term quality of life with patients of sepsis. ⋯ Serum concentrations GFAP and UCH-L1 early elevated and associated with sepsis-associated encephalopathy, poor prognosis and quality of life.
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Journal of critical care · Aug 2019
Observational StudyThe effect of emergency department crowding on lung-protective ventilation utilization for critically ill patients.
To measure effects of ED crowding on lung-protective ventilation (LPV) utilization in critically ill ED patients. ⋯ ED patients remain on suboptimal tidal volume settings with infrequent ventilator adjustments during the ED stay. Hospitals should focus on both systemic factors and bedside physician and/or respiratory therapist interventions to increase LPV utilization in times of ED boarding and crowding for all patients.
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Journal of critical care · Aug 2019
Multicenter Study Comparative Study Clinical TrialA comparison of very old patients admitted to intensive care unit after acute versus elective surgery or intervention.
We aimed to evaluate differences in outcome between patients admitted to intensive care unit (ICU) after elective versus acute surgery in a multinational cohort of very old patients (≥80 years; VIP). Predictors of mortality, with special emphasis on frailty, were assessed. ⋯ VIPs admitted to ICU after elective surgery evidenced favorable outcome over patients after acute surgery even after correction for relevant confounders. Frailty might be used to guide clinicians in risk stratification in both patients admitted after elective and acute surgery.