Journal of critical care
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Journal of critical care · Dec 2023
Review Meta AnalysisEffectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis.
To analyze the effectiveness of sleep interventions in reducing the incidence and duration of delirium in the ICU. ⋯ The current evidence suggests that non-pharmacological sleep interventions are not effective in preventing delirium in ICU patients. However, limited by the number and quality of included studies, future well-designed multicenter randomized controlled trials are still needed to validate the results of this study.
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Journal of critical care · Dec 2023
Review Meta AnalysisEffectiveness of sleep interventions to reduce delirium in critically ill patients: A systematic review and meta-analysis.
To analyze the effectiveness of sleep interventions in reducing the incidence and duration of delirium in the ICU. ⋯ The current evidence suggests that non-pharmacological sleep interventions are not effective in preventing delirium in ICU patients. However, limited by the number and quality of included studies, future well-designed multicenter randomized controlled trials are still needed to validate the results of this study.
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Journal of critical care · Dec 2023
ReviewAwake prone positioning in acute hypoxaemic respiratory failure: An international expert guidance.
Awake prone positioning (APP) of non-intubated patients with acute hypoxaemic respiratory failure (AHRF) has been inconsistently adopted into routine care of patients with COVID-19, likely due to apparent conflicting evidence from recent trials. This short guideline aims to provide evidence-based recommendations for the use of APP in various clinical scenarios. ⋯ APP should be routinely implemented in patients with COVID-19 receiving advanced respiratory support.
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Journal of critical care · Dec 2023
ReviewInflammatory biomarkers to predict the prognosis of acute bacterial and viral infections.
Mortality in acute infections is mostly associated with sepsis, defined as 'life-threatening organ dysfunction caused by a dysregulated host response to infection'. It remains challenging to identify the patients with increased mortality risk due to the high heterogeneity in the dysregulated host immune response and disease progression. ⋯ However, limited research investigated whether the prognostic potential of these biomarkers differs between bacterial and viral infections. In this narrative review, we provide an overview of the value of various inflammatory biomarkers for the prediction of mortality in bacterial and viral infections.
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Journal of critical care · Dec 2023
Meta AnalysisChoice of creep or maintenance fluid type and their impact on total daily ICU sodium burden in critically ill patients: A systematic review and meta-analysis.
Maintenance and hidden/creep fluids are a major source of fluid and sodium intake in intensive care unit (ICU) patients. Recent research indicates that low versus high sodium content maintenance fluids could decrease fluid and sodium burden. We conducted a systematic review (SR) with meta-analysis to summarize the impact of maintenance fluid choice on total daily sodium in ICU patients. ⋯ Using low sodium content maintenance/creep fluids substantially reduces daily sodium burden in adult ICU patients. Significant knowledge/research gaps exist regarding relevance and safety.