Perfusion
-
Randomized Controlled Trial
Increasing mean arterial pressure during cardiac surgery does not reduce the rate of postoperative acute kidney injury.
We hypothesized that the optimization of renal haemodynamics by maintaining a high level of mean arterial blood pressure (MAP) during cardiopulmonary bypass (CPB) could reduce the rate of acute kidney injury (AKI) in high-risk patients. ⋯ Maintaining a high level of MAP (on average) during normothermic CPB does not reduce the risk of postoperative AKI. It does not alter the length of hospital stay or the mortality rate.