Renal failure
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Review Meta Analysis
The dose of continuous renal replacement therapy for acute renal failure: a systematic review and meta-analysis.
To conduct a systematic review of the literature to summarize the best available evidence regarding the mortality and morbidity associated with differing dosing regimens of continuous renal replacement therapy (CRRT) for patients with acute renal failure (ARF) in an intensive care unit setting. ⋯ Increased dosing of CRRT is not associated with a decrease in mortality of patients with ARF in an intensive care unit setting.
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The purpose of this study was to investigate and compare the efficiency of propofol in the reduction of injury induced by free radicals in a rat model of renal ischemia/reperfusion (I/R). ⋯ Our results demonstrate that I/R injury was significantly reduced in the presence of propofol. The protective effects of propofol may be due to their antioxidant properties. These results may indicate that propofol anesthesia protects against functional, biochemical, and morphological damage better than control in renal I/R injury.