Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Anaesthetic requirements may be reduced following surgery employing cardiopulmonary bypass (CPB). This study, in dogs, determined the role of a) volatile agents (enflurane [E] vs isoflurane [I]), b) oxygenator (bubble [B] vs membrane [M]), and c) presence [FL] vs absence [NoFL] of an in-line arterial filter in the bypass circuit in altering anaesthetic requirements following CPB. ⋯ In dogs, MAC reduction following CPB was variable, not related to type of volatile agent employed, use of a membrane or bubble oxygenator, or presence or absence of an in-line arterial filter. The explanation for reductions in anaesthetic requirements following CPB in this model remains speculative.
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Randomized Controlled Trial Comparative Study Clinical Trial
Trial of three methods of intraoperative bupivacaine analgesia for pain after paediatric groin surgery.
To evaluate the relative effectiveness of three techniques of regional anaesthesia in the provision of postoperative analgesia in children. ⋯ All three methods achieved analgesia with 80% of the pain scores meeting our definition of satisfactory pain control. None of the techniques enjoyed any apparent advantage.
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Randomized Controlled Trial Clinical Trial
Interactions between nicardipine and enflurane, isoflurane, and sevoflurane.
During nicardipine induced hypotension, different inhalational anaesthetics may have different effects on haemodynamic variables, sympathetic function and drug metabolism. Therefore, the haemodynamic effects and pharmacokinetics of nicardipine were studied in the presence of the three inhalation anaesthetics enflurane, isoflurane and sevoflurane. ⋯ This study showed that the action of nicardipine is modified by different inhalational anaesthetic agents. Nicardipine has a prolonged duration of action in the presence of isoflurane and produces greater initial hypotension with sevoflurane.
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Clinical Trial
Continuous spinal anaesthesia using a standard epidural set for extracorporeal shockwave lithotripsy.
Continuous spinal anaesthesia (CSA) offers considerable advantages over "single shot" spinal or epidural anaesthesia since it allows titration of anaesthesia using small doses of local anaesthetics (LA). We evaluated the feasibility of CSA using a standard epidural set for extracorporeal shockwave lithotripsy (ESWL). ⋯ Continuous spinal anaesthesia, using a standard epidural set and hyperbaric bupivacaine is feasible for ESWL in high risk patients. Inadvertent dural puncture does not preclude CSA under these circumstances.