Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Randomized Controlled Trial Comparative Study Clinical Trial
Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients.
Little information is available regarding the use of patient-controlled sedation (PCS) among the elderly. This study evaluated the safety and efficacy of propofol PCS among elderly patients undergoing hip or knee arthroplasty. ⋯ Propofol PCS provides effective sedation. Using a propofol dose of 0.3 mg.kg-1, transient episodes of deeper sedation were noted more frequently among patients receiving PCS. These episodes did not require intervention but, suggest that this propofol PCS dose approaches the limit of safety and should be further reduced for some elderly patients.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Haemodynamic changes induced by two I:E ratios: a transoesophageal echocardiographic study.
To assess the effects of controlled ventilation with two I:E ratios on haemodynamic and left ventricular function in mechanically ventilated patients with moderate to severe respiratory disease, using fluctuation of the arterial pressure waveform and the changes in left ventricular areas obtained by transoesophageal echocardiography. ⋯ In this setting, EDA and SBPV allow beat-to-beat evaluation of left ventricular preload during change of I:E ratio. Switch from I:E 1:3 to 1:1 may be used as a rapid, safe and reversible test to estimate intravascular volume status assessed by changes in SBPV or EDA.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Granisetron reduces the incidence and severity of nausea and vomiting after laparoscopic cholecystectomy.
Postoperative nausea and vomiting (PONV) are commonly observed undesirable consequences of laparoscopic cholecystectomy. This study was undertaken to compare granisetron, a selective 5-hydroxytryptamine type 3 receptor antagonist, with droperidol for reducing the incidence and severity of PONV after laparoscopic cholecystectomy. ⋯ Granisetron is more effective than droperidol and placebo for reducing the incidence and severity of PONV after laparoscopic cholecystectomy.
-
Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of three regional anaesthesia techniques for outpatient knee arthroscopy.
The purpose of this study was to compare intraoperative conditions and postoperative pain control of three peripheral regional anaesthesia techniques for outpatient knee arthroscopic procedures. ⋯ Any of the three anaesthetic techniques tested provide reliable intraoperative patient and surgical conditions for outpatient knee arthroscopy. Patient discomfort postoperatively was considerable in all groups and requires further investigation.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Transdermal fentanyl system plus im ketorolac for the treatment of postoperative pain.
To assess the safety and efficacy of transdermal fentanyl plus im ketorolac vs im ketorolac alone in the treatment of postoperative pain. ⋯ The transdermal fentanyl delivery system plus ketorolac im was more effective in controlling post-operative pain than ketorolac im alone. The two treatment modalities were comparable in safety with no difference in serious adverse events.