Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Double-blind comparison of epidural ropivacaine 0.25% and bupivacaine 0.25%, for the relief of childbirth pain.
To evaluate the efficacy of ropivacaine 0.25% when administered epidurally for relief of labour pain and to compare it with bupivacaine 0.25%. ⋯ Ropivacaine 0.25%, when administered epidurally by intermittent top-ups for labour analgesia, was equally efficacious as bupivacaine 0.25%.
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Randomized Controlled Trial Comparative Study Clinical Trial
Heat conservation vs convective warming in adults undergoing elective surgery.
To determine the relative efficacy of heat conservation and convective warming in maintaining perioperative normothermia, (central temperature > or = 36 degrees C). ⋯ Patients receiving convective warming were more likely to leave the operating room normothermic, and had higher central temperatures during the first 30 min in the recovery room. The intergroup temperature differences were small, and by 60 min, had disappeared.
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Clinical Trial Controlled Clinical Trial
Clonidine decreases vasoconstriction and shivering thresholds, without affecting the sweating threshold.
This study was conducted to test the hypothesis that clonidine produces a dose-dependent increase in the sweating threshold and dose-dependent decreases in vasoconstriction and shivering thresholds. ⋯ The decreases in core temperature thresholds for cold responses and increased interthreshold range are consistent with the effects of several anaesthetic agents and opioids and is indicative of central thermoregulatory inhibition.
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Randomized Controlled Trial Clinical Trial
Propofol or midazolam for sedation and early extubation following cardiac surgery.
The purpose of this randomized, double-blind study was to evaluate the efficacy of midazolam and propofol for postoperative sedation and early extubation following cardiac surgery. ⋯ We conclude that midazolam and propofol are safe and effective sedative agents permitting early extubation in this selected cardiac patient population but propofol costs were higher.
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Randomized Controlled Trial Clinical Trial
Cardiac performance during unilateral lumbar spinal block after crystalloid preload.
The haemodynamic effects of crystalloid preload were evaluated in a randomised blind study in 20 ASA status I-II, 50-80 yr-old patients, undergoing unilateral spinal anaesthesia for leg surgery produced with low doses of hyperbaric bupivacaine. ⋯ Crystalloid preload influences cardiovascular function during spinal block, and may be useful when very low bupivacaine doses and lateral decubitus are used to achieve unilateral spinal block.