Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Randomized Controlled Trial Comparative Study Clinical Trial
Onset of spinal block is more rapid with isobaric than hyperbaric bupivacaine.
To compare isobaric with hyperbaric 9.75 mg bupivacaine injected intrathecally, and to evaluate the effects of subsequent injection of lidocaine 2% into the epidural space. ⋯ The block developed more rapidly in the isobaric group, but both isobaric and hyperbaric 9.75 mg bupivacaine produced adequate upper levels of analgesia for surgery. The effect of epidural injections of 3 ml lidocaine 2% was usually minimal.
-
Randomized Controlled Trial Clinical Trial
Patient supplemented epidural analgesia after major abdominal surgery with bupivacaine/fentanyl or ropivacaine/fentanyl.
To compare analgesic efficacy and occurrence of motor block and other side effects during patient supplemented epidural analgesia (PSEA) with either ropivacaine/fentanyl or bupivacaine/fentanyl mixtures. ⋯ Using a ropivacaine 0.2%/2 microg x ml(-1) fentanyl mixture for patient supplemented epidural analgesia after major abdominal surgery provided similar successful pain relief as bupivacaine 0.125%/2 microg x ml(-1) fentanyl, but patients receiving bupivacaine/fentanyl requested more supplemental.
-
Randomized Controlled Trial Clinical Trial
Transcutaneous electrical nerve stimulation does not augment combined spinal epidural labour analgesia.
The spinal portion of the combined spinal epidural technique (CSE) provides dramatic but limited labour analgesia. Transcutaneous Electrical Nerve Stimulation (TENS) has been noted to modulate pain, in part by the frequency of stimulation chosen. Because nerve action potentials are blocked by local anesthetics in a frequency dependent manner, we speculated that a TENS unit could increase the quality and duration of the spinal portion of a CSE. ⋯ In healthy labouring parturients, the application of a TENS unit did not alter the quality or duration of labour analgesia provided by the spinal portion of CSE analgesia.
-
Randomized Controlled Trial Clinical Trial
Midazolam premedication reduces propofol requirements for sedation during regional anesthesia.
Propofol is often used for sedation during spinal anesthesia. We investigated the effects of midazolam premedication on the propofol requirements and incidence of complications during sedation. ⋯ Midazolam premedication reduced propofol requirements and the incidence of intraoperative memory during sedation. These effects on sedation using propofol during spinal anesthesia are considered beneficial for patients.
-
Randomized Controlled Trial Clinical Trial
Epidural naloxone reduces pruritus and nausea without affecting analgesia by epidural morphine in bupivacaine.
To determine whether epidural naloxone preserved analgesia while minimizing side effects caused by epidural morphine. ⋯ Epidural naloxone reduced morphine-induced side effects in dose-dependent fashion without reversal of the analgesic effect.