Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Randomized Controlled Trial Clinical Trial
Epidural naloxone reduces intestinal hypomotility but not analgesia of epidural morphine.
Epidural morphine is associated with decreased bowel motility and increased transit time. Low doses of intravenous naloxone reduce morphine-induced pruritus without reversing analgesia, but the effect of epidural naloxone on bowel motility has not been studied. Therefore we evaluated bowel motility and analgesia when naloxone was co-administered with morphine into the epidural space. ⋯ Epidural naloxone reduces epidural morphine-induced intestinal hypomotility without reversing its analgesic effects.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Remifentanil and controlled hypotension; comparison with nitroprusside or esmolol during tympanoplasty.
To determine whether remifentanil, combined with propofol, could induce controlled hypotension, reduce middle ear blood flow (MEBF) measured by laser-Doppler flowmetry, provide a "dry" operative field, and could be compared with nitroprusside or esmolol combined with alfentanil and propofol. ⋯ Remifentanil combined with propofol enabled controlled hypotension, reduced middle ear blood flow and provided good surgical conditions for tympanoplasty with no need for additional use of a potent hypotensive agent.
-
Randomized Controlled Trial Clinical Trial
High concentration sevoflurane induction of anesthesia accelerates onset of vecuronium neuromuscular blockade.
To investigate neuromuscular block using accelography after administration of vecuronium under sevoflurane 8% induction and maintenance with sevoflurane 2% in adults. ⋯ Vital capacity inhalation induction of anesthesia with sevoflurane accelerates onset and prolongs duration of vecuronium neuromuscular block compared with propofol-fentanyl anesthesia.
-
Randomized Controlled Trial Clinical Trial
Nicorandil accelerates recovery of neuromuscular block caused by vecuronium.
To examine the effect of nicorandil, a K ATP channel agonist, on neuromuscular block caused by vecuronium in patients anesthetized with nitrous oxide, oxygen, isoflurane, and fentanyl. ⋯ Nicorandil accelerates recovery of neuromuscular block caused by vecuronium.
-
Randomized Controlled Trial Clinical Trial
Lateral recumbent head-down posture for epidural catheter insertion reduces intravascular injection.
The unintentional and unrecognized cannulation of an extradural vein is a potentially serious complication of an epidural anesthetic. The present study was undertaken to assess the incidence of blood vessel puncture related to epidural catheterization performed in three different body positions. ⋯ Adoption of the lateral recumbent head-down position for the performance of lumbar epidural blockade, in labour at term, reduces the incidence of lumbar epidural venous puncture.