Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Randomized Controlled Trial Clinical Trial
Dexamethasone prophylaxis of nausea and vomiting after epidural morphine for post-Cesarean analgesia.
To determine the minimum effective dose of dexamethasone in preventing nausea and vomiting associated with epidural morphine for post-Cesarean analgesia. ⋯ Dexamethasone, 5 mg i.v., is suggested as the minimum effective dose in preventing nausea and vomiting associated with epidural morphine for post-Cesarean analgesia.
-
Randomized Controlled Trial Clinical Trial
Dextromethorphan attenuation of postoperative pain and primary and secondary thermal hyperalgesia.
To determine the effect of 90 mg dextromethorphan (DM) p.o. vs placebo 90 min preoperatively, on the immediate and delayed postoperative course. ⋯ Compared with placebo, DM enabled reduction of postoperative analgesics consumption, improved well-being, and reduced sedation, pain intensity and primary and secondary thermal hyperalgesia.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Impact of the initial doses of rocuronium and pancuronium on subsequent maintenance for neuromuscular block.
To determine the impact of the neuromuscular blocking agent given for intubation on the duration of effect of multiple maintenance doses of pancuronium and rocuronium. ⋯ For combinations of rocuronium and pancuronium, the duration of twitch suppression after a maintenance dose is only dependent on the first agent given for the first two maintenance doses administered.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Gastric air tonometry during laparoscopic cholecystectomy: a comparison of two PaCO2 levels.
Pneumoperitoneum can cause disturbances in acid-base balance and splanchnic perfusion. We studied the effect of ventilation on acid-base balance and gastric mucosal tonometric values in patients undergoing laparoscopic cholecystectomy. ⋯ Despite inter-group differences in arterial and tonometric PCO2 and pH values during CO2 pneumoperitoneum, the patients did not develop splanchnic hypoperfusion detectable by air tonometric method, as indicated by normal PCO2 gap in both groups throughout the study.