Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Clinical Trial
Intranasal fentanyl provides adequate postoperative analgesia in pediatric patients.
To evaluate intranasally administered fentanyl for postoperative analgesia in pediatric patients. ⋯ The intranasal route provides a good alternative for administration of fentanyl in pediatric surgical patients.
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Randomized Controlled Trial Clinical Trial
Caudal anesthesia reduces the minimum alveolar concentration of enflurane for laryngeal mask airway removal in boys.
To investigate the effects of caudal analgesia on the minimal alveolar concentration of enflurane for laryngeal mask airway (LMA) smooth extubation (MACex). ⋯ In conclusion, caudal analgesia significantly reduced the LMA MACex of enflurane by approximately 29%. Possible mechanisms may be related to the analgesic effect of caudal blockade or to the sedative properties of neuraxial anesthesia.
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Randomized Controlled Trial Clinical Trial
The addition of tramadol to lidocaine does not reduce tourniquet and postoperative pain during iv regional anesthesia.
We conducted a prospective, randomized, double-blind study to determine whether the combination of tramadol with lidocaine 0.5% had an analgesic effect on tourniquet pain during iv regional anesthesia and also on postoperative pain. ⋯ We conclude, therefore, that for carpal tunnel operation under iv regional anesthesia, the combination of tramadol and lidocaine is not more effective than lidocaine alone.
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Randomized Controlled Trial Comparative Study Clinical Trial
Central nervous system side effects are less important after iv regional anesthesia with ropivacaine 0.2% compared to lidocaine 0.5% in volunteers.
Following release of a double tourniquet for intravenous regional anesthesia (IVRA), ropivacaine was shown to have a longer duration of action and less central nervous system (CNS) side effects than lidocaine. This study examines the correlation of CNS side effects to plasma levels of lidocaine 0.5% and ropivacaine 0.2% when injected intravenously for IVRA. ⋯ We observed a lower incidence of CNS side effects with ropivacaine as compared to lidocaine. Although ropivacaine's greater lipid solubility should, theoretically, lead to more CNS side effects, this was, likely, offset by slower release from tissues and lesser percentage of unbound (free) drug.