Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Comparative Study Clinical Trial
Patient-controlled analgesia with fentanyl provides effective analgesia for second trimester labour: a randomized controlled study.
To examine dose and lockout intervals for effective fentanyl patient-controlled analgesia (PCA) in second trimester genetic termination of pregnancy, and compare three different fentanyl PCA regimes with morphine PCA. ⋯ This study found PCA fentanyl 50 micro g with a lockout period of six minutes provided satisfactory analgesia for second trimester labour.
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Randomized Controlled Trial Clinical Trial
Neuromuscular block with vecuronium reduces the rapidly extracted auditory evoked potentials index during steady state anesthesia.
During clinical monitoring, vecuronium appeared to reduce the rapidly extracted auditory evoked potentials index (A-line ARX index or AAI) to some extent. A prospective and randomized study was designed to analyze this phenomenon. ⋯ Neuromuscular block with vecuronium reduces AAI in patients during steady state anesthesia without surgical stimuli, while BI(hx) is unaltered. The cut-off values of AAI for events should be determined according to the level of neuromuscular blockade when monitoring the depth of anesthesia/sedation.
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Review
Retrieving organs from non-heart-beating organ donors: a review of medical and ethical issues.
The increasing gap between numbers of individuals awaiting organ replacement surgery and the supply of organs available for transplant underpins attempts to increase the number of organs available. One practice, used in other countries, is the recovery of organs from non-heart-beating organ donors (NHBD). The purpose of this review is to discuss ethical issues surrounding the use of organs from these donors. ⋯ Canadian centres can learn from the difficulties encountered in other centres that have developed NHBD protocols. A moratorium on Canadian NHBD protocols should be considered until a National consensus reflecting Canadian values has been undertaken.
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Clinical Trial
Systolic pressure variation (Deltadown) can guide fluid therapy during pheochromocytoma surgery.
To date, no monitoring has proved its usefulness for both interpretation and treatment of arterial hypotension following pheochromocytoma resection. In this prospective observational study, we measured the negative component (Deltadown) of the respiratory systolic pressure variation in order to assess its ability to guide fluid therapy in 13 patients undergoing pheochromocytoma surgery. ⋯ During pheochromocytoma surgery, a Deltadown