Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial
Bupivacaine/ketamine is superior to intra-articular ketamine analgesia following arthroscopic knee surgery.
Centroneuraxial and parenteral administration of ketamine has been shown to produce analgesia. However, this analgesia is limited by adverse effects. The purpose of this study was to determine whether ketamine alone or in combination with bupivacaine provides superior pain relief after surgery in patients undergoing knee arthroscopy. ⋯ We conclude that intra-articular bupivacaine-ketamine combination provides better pain relief than intra-articular ketamine after day care arthroscopic knee surgery.
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Letter Randomized Controlled Trial
Lidocaine 2% with or without glucose 8% for spinal anesthesia for short orthopedic surgery.
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Randomized Controlled Trial
Gabapentin provides effective postoperative analgesia whether administered pre-emptively or post-incision.
We investigated the effects of pre-incision and post-incision administration of gabapentin on postoperative pain and fentanyl consumption associated with open donor nephrectomy. ⋯ Pre-incision administration of 600 mg gabapentin has no added benefit over post-incision administration in terms of pain scores and fentanyl consumption in subjects undergoing open donor nephrectomy.
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Randomized Controlled Trial
Brachial plexus block with midazolam and bupivacaine improves analgesia.
Adjuncts to local anesthetics for brachial plexus block may enhance the quality and duration of analgesia. Midazolam, a water-soluble benzodiazepine, is known to produce antinociception and enhance the effect of local anesthetics when given epidurally or intrathecally. The purpose of this study was to assess the effect of midazolam added to brachial plexus anesthesia. ⋯ Midazolam (50 microg x kg(-1)) in combination with 30 mL of bupivacaine (0.5%) hastened onset of sensory and motor block, and improved postoperative analgesia when used in brachial plexus block, without producing any adverse events.
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Randomized Controlled Trial
Low-dose intrathecal morphine does not delay early extubation after cardiac surgery.
This study was designed to examine the efficacy of low-dose intrathecal morphine (ITM) on extubation times and pain control after cardiac surgery. ⋯ Low-dose ITM for cardiac surgery did not delay early extubation, but it improved postoperative analgesia and pulmonary function.