Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Comparative Study
Analgesic effects of systemic midazolam: comparison with intrathecal administration.
Midazolam has antinociceptive effects when administered intrathecally, while its effects associated with systemic administration remain controversial. In the present study, the antinociceptive properties of systemically vs intrathecally administered midazolam were investigated in a rat model of thermal and inflammatory pain. ⋯ Systemically administered midazolam induced antinociception for inflammatory pain only, while intrathecal administration elicited antinociceptive effects on both acute thermal and inflammatory-induced pain.
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Review
Brief review: angiotensin converting enzyme inhibitors and angioedema: anesthetic implications.
Angiotensin converting enzyme inhibitors (ACEIs) are a group of drugs used to treat hypertension and heart failure, with additional benefits, such as cardiovascular and renal protection, in patients with diabetes. However, angioedema as a complication of ACEI therapy is under-recognized. As there are important implications for anesthesiologists and emergency medicine physicians, a review was undertaken to document the scope of the problem of ACEI-induced angioedema.. ⋯ In view of the widespread clinical indications and ever-increasing use of ACEI drugs, the potentially life-threatening adverse reaction of ACEI-associated angioedema, and its treatment, must be recognized by anesthesiologists and all clinicians involved in airway management.
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To establish Canadian guidelines for training in adult perioperative transesophageal echocardiography (TEE). ⋯ The Canadian guidelines for training in adult perioperative TEE reflect the unique Canadian practice profile in perioperative TEE and address the training requirements to obtain expertise in this field.
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To facilitate electrocardiography (ECG)-guided central venous catheter placement by observing the shape and size of the P wave at specific locations of a central venous catheter (CVC) tip. ⋯ During ECG-guided central venous catheterization, the tallest peaked P wave may be used to place the CVC tip at the SVC/RA junction, the normally-shaped P wave identifies the mid to upper SVC, and biphasic P waves identify RA localization.