Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial
Topical lidocaine and oral acetaminophen provide similar analgesia for myringotomy and tube placement in children.
Preoperative oral acetaminophen (30 mg x kg(-1)) was compared with topical 2% lidocaine ear drops for postoperative analgesia following bilateral myringotomy and tube placement (BMT) in children. ⋯ Topical lidocaine and oral acetaminophen in a dose of 30 mg x kg(-1) provide similar analgesia following BMT.
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Critically-ill patients who receive nondepolarizing neuromuscular blocking drugs (NMBDs) may be at risk of developing profound muscle weakness that may last for months after the NMBD is discontinued, especially when large cumulative doses of NMBDs and corticosteroids are co-administered to septic, mechanically ventilated patients. This review focuses on the etiology and clinical features of critical illness myopathy (CIM), summarizes specific risk factors for its development, and discusses strategies that might be used to attenuate or even prevent the development of this potentially devastating syndrome. ⋯ Recent guidelines recommend that NMBDs be used in critically ill patients only when absolutely necessary, that the depth of muscle paralysis be monitored to avoid overdosing and metabolite accumulation, and that drug administration be curtailed periodically to allow interruption of sustained NMBD effect.
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A laboratory investigation was undertaken to compare the in vivo antinociceptive effects of 2% liposomal formulations of prilocaine (PLC), lidocaine (LDC) and mepivacaine (MVC) compared to plain solutions of each of these three local anesthetics. ⋯ Ces résultats indiquent que les liposomes sont des systèmes de vecteurs de médicaments efficaces pour les anesthésiques locaux de durée moyenne. La MVC a surtout bénéficié, et la LDC le moins, de l'encapsulation liposomique, peut-être à cause de ses plus importantes propriétés vasodilatatrices.
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A survey was undertaken at a single Academic Health Sciences Centre to document the opinions of anesthesiologists regarding what variables are important to document on the anesthetic record. A subsequent chart review of anesthetic records was undertaken to determine the extent to which these anesthesiologists record the variables they consider important. ⋯ Les anesthésiologistes de McGill considèrent que de nombreuses variables préopératoires et peropératoires sont importantes à noter au dossier anesthésique. Une revue subséquente des dossiers a indiqué que beaucoup de ces variables ne sont pas constamment inscrites. La transmission des informations médicales liées à l'anesthésie serait améliorée si les anesthésiologistes notaient plus régulièrement les variables qu'ils jugent les plus importantes.