Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial
Priming with rocuronium accelerates neuromuscular block in children: a prospective randomized study.
To determine the effects of a priming technique with respect to onset time and duration of action of rocuronium (1.5 x ED(95), 2.0 x ED(95)) in a pediatric patient population. ⋯ Priming accelerated the onset of rocuronium in children. A priming interval of one minute and a cumulative dose of rocuronium 1.5 x ED(95) resulted in an onset of neuromuscular block comparable to a single dose of rocuronium (2.0 x ED(95)).
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Randomized Controlled Trial
Small dose spinal bupivacaine for Cesarean delivery does not reduce hypotension but accelerates motor recovery.
Maternal hypotension occurs in 60-94% of Cesarean deliveries with 10-15 mg spinal bupivacaine. Reduced doses of bupivacaine may decrease the incidence of hypotension, nausea, and vasopressor use. The primary objective of this study was to compare 4.5 mg and 12 mg doses of intrathecal bupivacaine on maternal hemodynamics. The secondary objective was to determine if anticipated reductions in side effects were reflected in increased patient satisfaction. ⋯ Intrathecal bupivacaine 4.5 and 12 mg yielded similar sensory block and side effects during Cesarean delivery. Patients receiving 4.5 mg did, however, experience significantly less motor blockade of shorter duration.
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Randomized Controlled Trial
Milrinone enhances systolic, but not diastolic function during coronary artery bypass grafting surgery.
To evaluate the effect of milrinone on diastolic function during coronary artery bypass grafting surgery (CABG). ⋯ Distinct from its effects on systolic function, milrinone administered before CPB is not with associated improved biventricular diastolic function in patients undergoing CABG.
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This retrospective study was designed to assess the intensity of postoperative pain in relation to the location of craniotomy. ⋯ This study shows that the intensity of postoperative pain in neurosurgery is affected by the site of craniotomy. Frontal craniotomy patients experienced the lowest pain scores, and required significantly less opioid than patients undergoing posterior fossa interventions.