Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Septic shock is the leading cause of multiple organ failure and mortality in intensive care units. This condition seems to be related to an overproduction of both pro- and anti-inflammatory mediators, leading to an immunological dysfunction. Therapeutic strategies aimed at reducing blood and tissue concentrations of these mediators have been developed. One of these techniques, based on extra-renal filtration, is called "coupled plasma filtration and adsorption". ⋯ Additional evidence is needed to clarify the role of this blood purification technique for the treatment of septic shock.