Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Review Meta Analysis Comparative Study
The effects of intranasal dexmedetomidine premedication in children: a systematic review and meta-analysis.
Intranasal dexmedetomidine premedication is a newly introduced method for reducing stress and anxiety before general anesthesia in children. We performed a meta-analysis to identify the effects of intranasal dexmedetomidine premedication in children. ⋯ Intranasal dexmedetomidine provided more satisfactory sedation at parent separation and reduced the need for rescue analgesics and the incidence of nasal irritation and postoperative nausea and vomiting when compared with other premedication treatments.