Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Caffeine is used daily by 85% of United States adults and caffeine withdrawal is a major cause of perioperative headache. Studies have shown that caffeine supplementation in chronic caffeinators reduces the incidence of perioperative headache. This narrative review discusses the perioperative implications of caffeine withdrawal and outlines the benefits of and strategies of caffeine supplementation in the perioperative period. It is time to "wake up and smell the coffee" on integration of caffeine into established enhanced recovery after surgery protocols as a mechanism to consistently provide perioperative caffeine replacement.
-
The objective of this study was to provide a synthesis of the interventions designed to reduce medication errors in anesthetized patients. ⋯ Multimodal interventions and improved labelling reduce medication errors in anesthetized patients.
-
The objective of this study was to provide a synthesis of the interventions designed to reduce medication errors in anesthetized patients. ⋯ Multimodal interventions and improved labelling reduce medication errors in anesthetized patients.
-
In this Continuing Professional Development module, we review the practical pharmacology of tranexamic acid and its clinical use in trauma, obstetrics, and major orthopedic surgery. ⋯ Tranexamic acid is an efficacious and safe pharmacological-based blood conservation technique in the management of clinically significant hemorrhage. All anesthesiologists should have a good understanding of the pharmacotherapeutic properties and perioperative role of tranexamic acid therapy both inside and outside of the operating room. The use of tranexamic acid is likely to continue to rise with endorsement by various clinical guidelines and healthcare organizations. Further quantitative research is needed to evaluate optimal dosing and drug efficacy in these clinical scenarios.