Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Review Meta Analysis
Comparison of analgesic modalities for patients undergoing midline laparotomy: a systematic review and network meta-analysis.
Midline laparotomy is associated with severe pain. Epidural analgesia has been the established standard, but multiple alternative regional anesthesia modalities are now available. We aimed to compare continuous and single-shot regional anesthesia techniques in this systematic review and network meta-analysis. ⋯ Single-shot AWB were only clinically effective for analgesia in the early postoperative period. Continuous regional anesthesia modalities increased the duration of analgesia relative to their single-shot counterparts. Epidural analgesia remained clinically superior to alternative continuous regional anesthesia techniques for the first 24 hr, but reached equivalence, at least with respect to static pain, with continuous AWB and WI by 48 hr.
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Review Meta Analysis
Iron supplementation for patients undergoing cardiac surgery: a systematic review and meta-analysis of randomized controlled trials.
Iron supplementation has been evaluated in several randomized controlled trials (RCTs) for its potential to increase baseline hemoglobin and decrease red blood cell transfusion during cardiac surgery. This study's main objective was to evaluate the current evidence for iron administration in cardiac surgery patients. ⋯ The current literature does not support or refute the routine use of iron therapy in cardiac surgery patients.