Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial
Efficacy of a propofol bolus against placebo to prevent cough at emergence from general anesthesia with desflurane: a randomized controlled trial.
Emergence from anesthesia is a critical period and cough can result in adverse effects. Propofol inhibits airway reflexes and when infused it reduces cough more than inhalation anesthesia does. We evaluated the effect of a propofol bolus given at emergence on the incidence of coughing following a desflurane-based anesthesia. ⋯ In the present trial, a propofol bolus administered at emergence did not reduce the incidence of cough occurring between T0 and T5 following a desflurane-based general anesthesia compared with placebo.
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Comment Letter Case Reports
Accidental infusion of tranexamic acid via a thoracic epidural catheter.
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Review Meta Analysis
Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
Postoperative sleep disturbances are common. Although several studies have examined the effect of melatonin on postoperative sleep disturbances, the results have not reached any definitive conclusion. We sought to conduct a systematic review to compare the effects of melatonin and melatonin agonists on postoperative sleep quality with those of placebo or no treatment in adult patients who underwent surgery under general or regional anesthesia. ⋯ PROSPERO (CRD42020180167); registered 27 October 2022.
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Randomized Controlled Trial
A hood shield reduces postdoffing contamination during simulated COVID-19 airway management: an exploratory, simulation-based randomized study.
SARS-CoV-2 poses a significant occupational health threat to health care workers performing aerosol-generating medical procedures, with a threefold increased risk of a positive test and predicted infection compared with the general population. Nevertheless, the personal protective equipment (PPE) configuration that provides better protection with lower contamination rates is still unknown. ⋯ ClinicalTrials.gov (NCT04373096); registered 4 May 2020.