Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Meta Analysis
Prophylactic tranexamic acid in Cesarean delivery: an updated meta-analysis with a trial sequential analysis.
Postpartum hemorrhage (PPH) is a leading cause of maternal mortality worldwide. Although several studies on the prophylactic use of tranexamic acid (TXA) in parturients undergoing Cesarean delivery have been published, conflicting results raise questions regarding its use. Thus, we aimed to investigate the safety and efficacy of PPH prophylaxis with TXA. ⋯ PROSPERO (CRD42023422188); first submitted 27 April 2023.