Critical care medicine
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Critical care medicine · Oct 1999
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialContinuous plasmafiltration in sepsis syndrome. Plasmafiltration in Sepsis Study Group.
To assess the effect of plasmafiltration (PF) on biochemical markers of inflammation, cytokines, organ dysfunction, and 14-day mortality in human sepsis. ⋯ PF caused a significant attenuation of the acute-phase response in sepsis. There was no significant difference in mortality, but there was a trend toward fewer organs failing in the PF group that suggests that this procedure might be beneficial.