Critical care medicine
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Critical care medicine · Jan 2002
Randomized Controlled Trial Multicenter Study Clinical TrialRandomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome.
To determine whether the administration of lisofylline (1-[5R-hydroxyhexyl]-3,7-dimethylxanthine) would decrease mortality in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). ⋯ In this study, there was no evidence that lisofylline had beneficial effects in the treatment of established ALI/ARDS.