Critical care medicine
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Critical care medicine · Aug 2002
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialCandidemia as a cause of septic shock and multiple organ failure in nonimmunocompromised patients.
To describe outcomes of septic shock and multiple organ failure arising from candidemia. ⋯ Candidemia with septic shock is infrequent in nonimmunocompromised patients but has a very high mortality rate, a high likelihood of associated multiple organ failure, and possibly a delayed recovery from multiple organ failure. Patients with candidemic septic shock are more likely to have underlying renal failure at baseline.
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Critical care medicine · Aug 2002
Practice Guideline Multicenter Study Comparative Study GuidelineManagement of severe head injury: institutional variations in care and effect on outcome.
The purpose of this study was three-fold: a) to examine variations in care of patients with severe head injury in academic trauma centers across the United States; b) to determine the proportion of patients who received care according to the Brain Trauma Foundation guidelines; and c) to correlate the outcome from severe traumatic brain injury with the care received. ⋯ Considerable national variation in the care of severely head-injured patients persists. An "aggressive" management strategy is associated with decreased mortality rate for patients with severe head injury, with no significant difference in functional status at discharge among survivors.