Critical care medicine
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Critical care medicine · Feb 2007
Meta AnalysisTopical chlorhexidine for prevention of ventilator-associated pneumonia: a meta-analysis.
To assess the efficacy of topical chlorhexidine for prevention of ventilator-associated pneumonia (VAP) in a meta-analysis. ⋯ Our analysis showed that topical chlorhexidine is beneficial in preventing VAP; the benefit is most marked in cardiac surgery patients. A large randomized trial is needed to determine the impact of topical chlorhexidine on mortality.