Critical care medicine
-
Critical care medicine · Nov 2011
Randomized Controlled Trial Multicenter StudyEffect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: open-label, randomized study.
To investigate whether the use of pravastatin reduces the frequency of ventilator-associated pneumonia and whether it is related to favorable outcomes in critical care patients. ⋯ This study provides evidence that pravastatin may favorably affect the outcome of critical care patients.
-
Critical care medicine · Nov 2011
Multicenter StudyAssociation of prehospitalization aspirin therapy and acute lung injury: results of a multicenter international observational study of at-risk patients.
To evaluate the association between prehospitalization aspirin therapy and incident acute lung injury in a heterogeneous cohort of at-risk medical patients. ⋯ After adjusting for the propensity to receive aspirin therapy, no statistically significant associations between prehospitalization aspirin therapy and acute lung injury were identified; however, a prospective clinical trial to further evaluate this association appears warranted.