Critical care medicine
-
Critical care medicine · Jun 2013
Review Meta AnalysisThe effect of selenium therapy on mortality in patients with sepsis syndrome: a systematic review and meta-analysis of randomized controlled trials.
Patients with sepsis syndrome commonly have low serum selenium levels. Several randomized controlled trials have examined the efficacy of selenium supplementation on mortality in patients with sepsis. ⋯ In patients with sepsis, selenium supplementation at doses higher than daily requirement may reduce mortality. We observed no impact of selenium on ICU length of stay or risk of nosocomial pneumonia.
-
Critical care medicine · Jun 2013
Review Meta AnalysisPhysical therapy for the critically ill in the ICU: a systematic review and meta-analysis.
The purpose of this systematic review was to review the evidence base for exercise in critically ill patients. ⋯ Physical therapy in the ICU appears to confer significant benefit in improving quality of life, physical function, peripheral and respiratory muscle strength, increasing ventilator-free days, and decreasing hospital and ICU stay. However, further controlled trials of better quality and larger sample sizes are required to verify the strength of these tentative associations.