Critical care medicine
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Critical care medicine · Nov 2017
Randomized Controlled Trial Multicenter StudyBrain Oxygen Optimization in Severe Traumatic Brain Injury Phase-II: A Phase II Randomized Trial.
Brain tissue oxygentation monitoring after severe traumatic brain injury may improve mortality and neurological morbidity compared with ICP monitoring alone.
pearl -
Critical care medicine · Nov 2017
Review Meta AnalysisAntifungal Prevention of Systemic Candidiasis in Immunocompetent ICU Adults: Systematic Review and Meta-Analysis of Clinical Trials.
The aim of this study was to identify the impact of antifungal prevention in critically ill immunocompetent adult patients on mortality and subsequent infection. ⋯ Antifungal prevention of systemic candidiasis in immunocompetent critically ill adults did not reduce mortality and may have decreased secondary fungal infection rates. However, significant publication bias was present.
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Critical care medicine · Nov 2017
Review Meta AnalysisExtracorporeal Circulatory Support in Acute Coronary Syndromes: A Systematic Review and Meta-Analysis.
Extracorporeal circulatory support is a life-saving technique, and its use is increasing in acute coronary syndromes. A meta-analysis on pooled event rate of short-term mortality and complications of acute coronary syndrome patients treated with extracorporeal circulatory support was performed. ⋯ There is still a high rate of short-term mortality and complications in acute coronary syndrome patients treated with extracorporeal circulatory support. New studies are needed to optimize and standardize extracorporeal circulatory support.