Critical care medicine
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Critical care medicine · Jan 2025
ReviewInduction Agents for Tracheal Intubation in Critically Ill Patients.
Concise definitive review of the use of induction agents in critically ill patients undergoing tracheal intubation and their association with outcomes. ⋯ Although no definitive conclusions can be drawn based on the available evidence, recent evidence pointed out the potential negative effect of etomidate on survival and the association of propofol with cardiovascular instability. Ketamine may be considered the drug with a safer profile, widespread availability and low cost but future research should provide definitive data on optimal drug selection, its dosage in the context of critical illness and concomitant interventions to minimize the risk of peri-intubation complications.