The Journal of head trauma rehabilitation
-
J Head Trauma Rehabil · Jul 2010
Review Meta AnalysisCan low serum levels of S100B predict normal CT findings after minor head injury in adults?: an evidence-based review and meta-analysis.
To determine whether low levels of S100B in serum can predict normal computed tomography (CT) findings after minor head injury (MHI) in adults. ⋯ Low serum S100B levels accurately predict normal CT findings after MHI in adults. S100B sampling should be considered in MHI patients with no focal neurological deficit, an absence of significant extracerebral injury, should be taken within 3 hours of injury, and the cutoff for omitting CT set at less than 0.10 microg/L. Care givers should also be aware of other clinical factors predictive of intracranial complications after MHI.