Palliative medicine
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Palliative medicine · Oct 2006
Randomized Controlled Trial Comparative StudyAtropine drops for drooling: a randomized controlled trial.
Drooling occasionally occurs in cancer patients, impairing their quality of life. Recommended treatment includes the use of anticholinergic drugs, but there is a lack of scientific evidence supporting it; some recent reports tested the use of sublingual atropine, and further controlled studies have been recommended. ⋯ This study failed to demonstrate the effectiveness of atropine over placebo in this population; we provide further discussion of results.