Gastroenterology clinics of North America
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Gastroenterol. Clin. North Am. · Mar 2011
ReviewEmerging pharmacological therapies for the irritable bowel syndrome.
The irritable bowel syndrome (IBS) is a symptom-based disorder defined by the presence of abdominal pain and altered bowel habits. Clinical presentations of IBS are diverse, with some patients reporting diarrhea, some constipation, and others a mixture of both. ⋯ This fact has important implications for the choices and efficacy of IBS treatment. This article reviews the IBS drugs that have reached phase II or III clinical trials.