Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Jan 2006
Meta AnalysisMeta-analysis: Smectite in the treatment of acute infectious diarrhoea in children.
Although not currently recommended, dioctahedral smectite (smectite) is commonly used to treat acute infectious diarrhoea in many countries. ⋯ Smectite may be a useful adjunct to rehydration therapy in treating acute paediatric gastroenteritis. However, the results of this meta-analysis should be interpreted with caution as most of the included studies had important limitations. Cost-effectiveness analyses should be undertaken before routine pharmacological therapy with smectite is recommended.