Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Sep 2006
Randomized Controlled TrialDouble-blind, randomized, placebo-controlled study to evaluate the effects of tegaserod on gastric motor, sensory and myoelectric function in healthy volunteers.
The effects of tegaserod on gastric accommodation and postprandial satiety remain unclear. ⋯ While tegaserod decreased proximal gastric volume change after a meal, it does not appear to have significant effects on gastric motor and sensory function in healthy individuals. Further studies are required in patients with disturbances of gastric motor and sensory function.