Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Jun 2009
Randomized Controlled Trial Multicenter StudyGhrelin receptor agonist (TZP-101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis.
TZP-101 is a synthetic, selective ghrelin agonist in development for gastroparesis. ⋯ This proof-of-concept study demonstrates that the ghrelin agonist TZP-101 is well-tolerated in diabetes patients with moderate-to-severe chronic gastroparesis and shows statistically significant improvements in gastric emptying.