Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Jun 2012
Meta AnalysisMeta-analysis: probiotics in antibiotic-associated diarrhoea.
Diarrhoea is a common occurrence in association with antibiotic administration. Earlier studies and meta-analyses have suggested that probiotic administration reduces the incidence of antibiotic-associated diarrhoea (AAD). ⋯ This updated meta-analysis confirms earlier results supporting the preventive effects of probiotics in AAD.
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Aliment. Pharmacol. Ther. · Jun 2012
Meta AnalysisMeta-analysis: nonsteroidal anti-inflammatory drugs in biliary colic.
Biliary colic is a common manifestation of cholelithiasis, developing in about one-third of patients. Even if nonsteroid anti-inflammatory drugs (NSAIDs) have widely been used to relieve biliary pain, there is a lack of systematic review of treatments on this issue. ⋯ In patients with biliary colic NSAIDs are the first-choice treatments as they control pain with the same efficacy of opioids and significantly reduce the proportion of patients with severe complications. However, the lack of high-quality RCTs and the presence of consistent heterogeneity among studies may partially flaw these results.