Paediatric and perinatal epidemiology
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Paediatr Perinat Epidemiol · Nov 2013
Randomized Controlled Trial Multicenter StudyA randomised trial to evaluate the effects of low-dose aspirin in gestation and reproduction: design and baseline characteristics.
Low-dose aspirin (LDA) has been proposed to improve pregnancy outcomes in couples experiencing recurrent pregnancy loss. However, results from studies of LDA on pregnancy outcomes have been inconsistent, perhaps because most studies evaluated LDA-initiated post-conception. The purpose of the Effects of Aspirin in Gestation and Reproduction (EAGeR) trial was to determine whether preconception-initiated LDA improves livebirth rates in women with one to two prior losses. ⋯ We describe the study design, recruitment, data collection, and baseline characteristics of participants enrolled in EAGeR, which aimed to determine the effect of LDA on livebirth and other pregnancy outcomes in these women.