Archives of gynecology and obstetrics
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Arch. Gynecol. Obstet. · Dec 2011
Randomized Controlled Trial Comparative StudyCarbetocin versus syntometrine in the management of third stage of labor following vaginal delivery.
To assess and compare the efficacy and safety of a single intramuscular dose of carbetocin to a single intramuscular dose of syntometrine in managing the third stage of labor following vaginal delivery among women with low risk factors for postpartum hemorrhage. ⋯ Single dose of intramuscular carbetocin 100 μg may be more effective as compared to a single intramuscular dose of syntometrine in reducing postpartum blood loss with a smaller drop in hemoglobin levels and less adverse effects.
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Arch. Gynecol. Obstet. · Dec 2011
Randomized Controlled TrialThe effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy.
Although intravenous acetaminophen is commonly used for the management of postoperative pain, very limited evidence supports the usefulness of preoperative administration. The aim of this study was to determine the analgesic effect of preoperative acetaminophen on opioid consumption, pain scores, and side effects in patients receiving an elective abdominal hysterectomy. ⋯ Premedication with acetaminophen reduced hydromorphone consumption and opioid-related side effect in patients undergoing abdominal hysterectomy, but did not significantly reduce pain intensity.