Archives of gynecology and obstetrics
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Arch. Gynecol. Obstet. · May 2017
Randomized Controlled TrialSingle bolus low-dose of ketamine does not prevent postpartum depression: a randomized, double-blind, placebo-controlled, prospective clinical trial.
Postpartum depression is a common complication of childbirth. In the last decade, it has been suggested that subdissociative-dose ketamine is a fast-acting antidepressant. We aimed to investigate the efficacy of low-dose ketamine administered during caesarean section in preventing postpartum depression. ⋯ Intra-operative low-dose ketamine (0.25 mg/kg) does not have a preventive effect on postpartum depression.