Clinical transplantation
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Clinical transplantation · May 2016
Does the development of chronic kidney disease and acute kidney injury affect the prognosis after living donor liver transplantation?
Chronic kidney disease (CKD) and acute kidney injury (AKI) have been discussed as complications following living donor liver transplantation (LDLT). The aim of this study was to clarify the relationships among CKD, AKI, and the prognosis after LDLT. ⋯ Recognizing the risk factors and careful management for preventing both AKI and CKD may improve the prognosis of patients following LDLT.
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Clinical transplantation · Apr 2016
Pulmonary hypertension as a risk factor of mortality after lung transplantation.
Pulmonary hypertension (PH) is recognized as a risk factor in lung transplantation as reflected in the lung allocation score (LAS). We examined the impact of PH on outcome after lung transplantation, with special emphasis on pre- and post-capillary PH. ⋯ Post-capillary PH was present in 11% and pre-capillary PH in 41% of the transplant cohort. Post-capillary PH and pre-capillary PH were associated with inferior 90-d survival, but long-term survival was unaffected.
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Clinical transplantation · Apr 2016
Effect of donor cardiac arrest and arrest duration on outcomes of lung transplantation.
Limited data are available about lung transplantation (LTx) from donors suffering cardiac arrest (CA) prior to actual donation. ⋯ Transplantation of lungs from donors with a history of CA is safe and feasible. Longer duration of cardiac arrest may improve the outcomes after the LTx in terms of survival and freedom from BOS.
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Clinical transplantation · Apr 2016
A rare indication for lung transplantation - pulmonary alveolar microlithiasis: institutional experience of five consecutive cases.
Pulmonary alveolar microlithiasis (PAM) is a rare lung disease caused by calcifications within the alveolar space. The only known effective treatment for an end-stage PAM is lung transplantation (LuTX). ⋯ Lung transplantation is a feasible therapy option in patients with end-stage PAM showing good post-operative results comparable to other indications for LuTX.
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Clinical transplantation · Apr 2016
Dual kidney transplants from adult marginal donors successfully expand the limited deceased donor organ pool.
The need to expand the organ donor pool remains a formidable challenge in kidney transplantation (KT). The use of expanded criteria donors (ECDs) represents one approach, but kidney discard rates are high because of concerns regarding overall quality. Dual KT (DKT) may reduce organ discard and optimize the use of kidneys from marginal donors. ⋯ Dual kidney transplantation using kidneys from adult marginal DDs that otherwise might be discarded offer a viable option to counteract the growing shortage of acceptable single kidneys. Excellent medium-term outcomes can be achieved and waiting times can be reduced in a predominantly older recipient population.