Brain injury : [BI]
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Brain injury : [BI] · Jan 2012
Multiple indicators model of long-term mortality in traumatic brain injury.
To examine the prognostic ability of protein S100B, neuron-specific enolase (NSE) and glial fibrillary acid protein (GFAP) for prediction of 1-year mortality in patients with traumatic brain injury (TBI) in relation to clinical and radiological characteristics of TBI. ⋯ Mortality at 1-year post-TBI is accurately predicted by the combination of GFAP and S100B concentration and clinical and radiological characteristics at admission or in the acute post-injury period.
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Brain injury : [BI] · Jan 2012
Implications of neurophysiological parameters in persons with severe brain injury with respect to improved patient outcomes: a retrospective review.
To determine whether neurophysiologic parameters-intracranial pressure (ICP), mean arterial pressure (MAP), cerebral perfusion pressure (CPP), partial brain tissue oxygenation (PbtO(2)) and pressure reactivity index (PRx, calculated)-captured during the management of traumatic brain injury (TBI) have a relationship to patient outcome. ⋯ Improved autoregulation was associated with PRx values near zero. Controlling those parameters that affect PRx, namely MAP, ICP and CPP and more importantly cerebral oxygen perfusion (COP), would likely increase the probability of a better outcome while guarding against secondary insult.
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Brain injury : [BI] · Jan 2012
Healthcare and disability service utilization in the 5-year period following transport-related traumatic brain injury.
To describe the type, intensity and direct cost of healthcare and disability services used following transport-related traumatic brain injury (TBI). ⋯ Healthcare service utilization and the economic burden of TBI are substantial. Injury compensation data provides a unique opportunity to explore patterns of healthcare usage post-injury, which is important for the planning and management of resources.
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Brain injury : [BI] · Jan 2012
Comparative StudyThe reliability of magnetic resonance imaging in traumatic brain injury lesion detection.
This study compares inter-rater-reliability, lesion detection and clinical relevance of T2-weighted imaging (T2WI), Fluid Attenuated Inversion Recovery (FLAIR), T2*-gradient recalled echo (T2*-GRE) and Susceptibility Weighted Imaging (SWI) in Traumatic Brain Injury (TBI). ⋯ T2*-GRE and SWI are more sensitive than T2WI and FLAIR in detecting (haemorrhagic) traumatic punctate lesions. The correlation between number of punctate lesions on T2*-GRE/SWI and the GCS indicates that haemorrhagic lesions are clinically relevant. The considerable inter-rater-disagreement in this study advocates cautiousness in interpretation of punctate lesions using T2WI and FLAIR.
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Brain injury : [BI] · Jan 2012
Ability of S100B to predict severity and cranial CT results in children with TBI.
To evaluate the ability of S100B to predict severity of TBI and abnormal cranial CT results for children with TBI. ⋯ For children following TBI, S100B appears to predict severity of TBI; however, it may not be clinically useful as an independent screening test to select children with mild TBI who need a cranial CT.