International journal of geriatric psychiatry
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Int J Geriatr Psychiatry · Jan 2015
Randomized Controlled Trial Multicenter StudyMemantine improves attention and episodic memory in Parkinson's disease dementia and dementia with Lewy bodies.
In both dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), attentional dysfunction is a core clinical feature together with disrupted episodic memory. This study evaluated the cognitive effects of memantine in DLB and PDD using automated tests of attention and episodic memory. ⋯ These are the first substantial improvements on cognitive tests of attention and episodic recognition memory identified with memantine in either DLB or PDD.