Toxicology
-
Exposure to cadmium and other pollutants is a major environmental problem. Cadmium is causing acute liver injury but the mechanism of hepatotoxicity is poorly understood. The present study aimed to assess the possible reasons by which cadmium causes liver toxicity. ⋯ Also, selenium can be used as a protective agent against Cd-toxicity. This study could provide a possible explanation to hepatotoxicity resulting from exposure to cadmium in the environment. In addition, selenium could ameliorate cadmium-induced hepatotoxicity since it reduced MDA levels and increased the activities of antioxidant enzymes in this tissue.