Lung cancer : journal of the International Association for the Study of Lung Cancer
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Meta Analysis
A meta-analysis of adjuvant EGFR-TKIs for patients with resected non-small cell lung cancer.
We performed this meta-analysis to compare adjuvant EGFR-TKIs with a placebo or adjuvant chemotherapy among patients with resected non-small cell lung cancer (NSCLC). ⋯ For patients with resected NSCLC harboring EGFR mutations, treatment with an adjuvant EGFR-TKI was superior to that of a placebo or chemotherapy in terms of DFS. Treatment with adjuvant EGFR-TKIs were not effective among patients with wild type EGFR NSCLC.