Clinical rehabilitation
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Clinical rehabilitation · Feb 2000
Randomized Controlled Trial Clinical TrialA double-blind placebo-controlled study of botulinum toxin in upper limb spasticity after stroke or head injury.
To assess dose-response relationships to a single dose of botulinum toxin 'A' in upper limb spasticity associated with stroke or head injury. ⋯ Botulinum toxin produced beneficial effects in spasticity and passive range of movement in the hemiplegic upper limb. Increasing the dose increased the magnitude of response for impairments in some muscle groups but had little effect on duration of response.