Nutrition
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The goal of this study was to investigate the effects of a high-fat diet supplemented with fish oil or olive oil, fed to C57BL/6J mice for an extended period, on metabolic features associated with type 2 diabetes. ⋯ Mice fed a high-fat diet supplemented with fish oil improved metabolic features associated with type 2 diabetes such as impaired glucose tolerance and hepatic steatosis.
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The fetal and neonatal environments are important determinants of disease risk in adult life. The aim of this study was to determine whether maternal green tea extract (GTE) intake during lactation affects the expression and activity of adenosine monophosphate-activated protein kinase (AMPK) in the kidneys of male offspring of protein-restricted dams during gestation. ⋯ GTE intake during lactation modulates AMPK, Akt, and mTOR expression in the kidneys of the adult male offspring of dams fed a protein-restricted diet and may induce long-term alterations in the expressions of these proteins in the kidneys.
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Several studies assessed the effect of glycemic index (GI) and glycemic load (GL) on energy intake in children but findings are not consistent in this regard. The aim of this study is to summarize and assess the evidence for the effect of GI and GL on energy intake by conducting a meta-analysis on published randomized clinical trials. ⋯ Consuming LGI diet (not LGL) has favorable effect on reducing energy intake and obesity, subsequently.
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Approximately 45% of the elderly population suffers from chronic kidney disease (CKD). The onset and the course of CKD can be ameliorated to a significant degree by several interventions, such as lowering blood pressure and serum lipid levels and achieving optimal glucose control in diabetes. ⋯ However, in the elderly, feasibility and compliance to LPD could be difficult and its effects are uncertain. In this contribution, we discuss the usefulness and the barriers of LPD regimen in the elderly.