Nutrition
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Randomized Controlled Trial Clinical Trial
Early nasojejunal feeding in acute pancreatitis is associated with a lower complication rate.
We investigated the effect of early jejunal feeding on septic complications and mortality rate in patients with acute pancreatitis in a two-phase, prospective, controlled study. ⋯ We believe that the combination of early enteral nutrition and selective, adequate antibiotic prophylaxis may prevent multiple organ failure in patients with acute pancreatitis.
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Randomized Controlled Trial Clinical Trial
Glutamine supplementation and GH/IGF-I treatment in critically ill patients: effects on glutamine metabolism and protein balance.
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Randomized Controlled Trial Clinical Trial
Enforced mobilization, early oral feeding, and balanced analgesia improve convalescence after colorectal surgery.
A postoperative regimen using a multimodal approach with enforced mobilization and early oral nutrition has been reported to improve convalescence but has not been compared with other postoperative regimens. ⋯ This active per- and postoperative regimen based on a multimodal approach improved ambulation time and muscle function during admission and late convalescence.
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Randomized Controlled Trial Clinical Trial
Influence of polymeric enteral nutrition supplemented with different doses of glutamine on gut permeability in critically ill patients.
To evaluate the effect of glutamine-supplemented polymeric enteral formulas on the recovery of gut-permeability abnormalities in critically ill patients. ⋯ Even though polymeric enteral nutrition was associated with a significant improvement in the L/M ratio, glutamine supplementation did not show a specific influence in improving recovery of gut permeability in critically ill patients.
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Randomized Controlled Trial Comparative Study Clinical Trial
Jejunal feeding, even when instituted late, improves outcomes in patients with severe pancreatitis and peritonitis.
This study assessed the feasibility and effectiveness of jejunal feeding (JF) after surgery due to secondary peritonitis or failed conservative therapy of severe pancreatitis. Of 60 patients, 30 were randomly assigned to receive postoperative JF and the remaining 30 constituted the control group. Acute Physiology and Chronic Health Evaluation II, nutritional intake, systemic inflammatory response syndrome, and outcomes were measured. ⋯ JF resulted in 3.3% mortality as opposed to 23.3% in the control group (P = 0.05). In conclusion, JF is feasible and effective in postoperative treatment of patients due to secondary peritonitis or severe pancreatitis. Improved bowel and peritoneal function could be the main impact of JF.